Jerzy Haber Institute of Catalysis and Surface Chemistry PAS invites applications for an Adiunct (post-doc) in the Theoretical and Experimental Biocatalysis group. The candidates who meet the conditions stated in the act “Ustawa o Polskiej Akademii Nauk” dated 30 April 2010 (Dz.U. 2018 poz. 1475 z póź. zm.), art 89. Ust. 4 for the position of Research Assistant are encouraged to apply for the position.
The candidate will participate in research within the OPUS 28 research project “Design of enzymes catalysing interfacial solid/liquid reaction” no 2024/55/B/ST4/02371, conducted in the Theoretical and Experimental Biocatalysis group in close collaboration with the group of Prof. Artur Góra from the Silesian University of Technology, concerning hydrolytic enzymes capable of cleaving ester, amide, and urethane bonds in synthetic polymers. According to the short description of the project: „The experimental part will be dedicated to: … v) design of a set of proteins for deep polyurethane degradation, vi) design of chimeric proteins with high affinity and catalytic efficiency toward heterogeneous surface.”
In particular, the Assistant’s responsibilities will include:
- protein production by overexpression in E. coli,
- protein purification using affinity chromatography and molecular filtration,
- studies of rapid enzymatic kinetics using stopped-flow or rapid freeze quench methods,
- protein crystallization,
- preparing scientific publications.